Finance hydroquinone nails Other skin products & problems Podcast

Is Hoof Maker cream for horses really good for your nails? Episode 111

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Is Dr. Varon’s pores and skin bleaching system protected?

Sarah asks…I’ve some questions on Dr. Varon’s pores and skin bleaching system. It makes use of 2% hydroquinone. Is it protected to maintain utilizing?

First let’s speak about pores and skin bleaching actives. Hydroquinone, like many different actives, HQ ,like many pores and skin lightening elements, is a phenolic compound. Meaning it accommodates a 6 carbon ring with an OH group hooked up. This construction permits it to inhibit melanin synthesis by appearing as a substrate for tyrosinase.

Tyrosine, an amino acid, is acted upon by the enzyme tyrosine to type melanin. These phenolic compounds “interrupt” this response by giving the tyrosine one thing else to connect to. That means the tyrosine by no means makes melanin particles. Based mostly on the analysis we’ve seen, nothing works higher than HQ – it’s thought-about the gold commonplace for pores and skin lightening. Yow will discover extra particulars should you return and take a look at Episode 35.

Is HQ protected? There have been research that raised most cancers considerations however they have been based mostly on oral or injected software and there have been no medical research or instances of pores and skin most cancers associated to topical HQ use. Subsequently, the Worldwide Company for Analysis on Most cancers (IARC) considers hydroquinone as “not classifiable” as to its carcinogenicity in people. It may, nevertheless, trigger a pores and skin discoloring situation often known as Och-ron-osis and that’s certainly one of causes that regulatory our bodies in different nations have banned HQ for over-the-counter use. It has needs to be prescribed by a physician which helps forestall the sort of long run abuse that may result in that everlasting discoloration.

Within the US The Meals and Drug Administration (FDA) has even proposed banning over-the counter pores and skin bleaching brokers containing hydroquinone however as of proper now it’s nonetheless out there.

This can be a essential level – it’s a fable that’s it’s “banned” in different nations, it’s really simply restricted to prescription use. Europe and Asia presently permit hydroquinone at 2-5% focus by prescription. The drug is valued worldwide however is regulated to guard towards misuse and dangerous formulations.

So, what about Dr Varon’s product? We have been intrigued once we examine his Pores and skin Bleaching system which claims to be “the first and only skin care system to remove blemishes and dark discolorations from the skin.” It’s inconceivable how they will make such a declare since HQ is an over-the-counter drug. That makes me very suspicious.

The system truly consists of three merchandise:

  • Step 1 Brightening Lotion (1 oz.)
  • 
Step 2 Dermal Remedy (1 oz.)
  • Step Three Liquid Microdermabrasion (1 oz.)

The system prices about 20 bucks which isn’t too dangerous till you understand you solely get one 1 ouncestube of every product. However you don’t use them up on the similar price. You’re supposed to make use of the Brightening lotion twice per day, the Dermal Remedy you employ as soon as a day and the Liquid Microderm product you employ 2 or Three occasions per week. So in a short time you’ll run out of the primary product and also you’ll have to purchase the complete package to get extra. You’re in all probability higher off shopping for one other 2% HQ cream after which utilizing different merchandise.

Is it protected? Sure, apart from the considerations we simply mentioned. Is it the perfect product to purchase? In all probability not.

Lively Elements: Hydroquinone (2%) Objective: Bleach
Inactive Elements:
Step 1: Water, Isoproply Palmitate, Glycolic Acid, Cyclomethicone, Azelaic Acid, Kojic Dipalmitate, PEG-100 Stearate, Arbutin, Potassium Hydroxide, Cetyl Alcohol, Glyceryl Stearate, Myristyl Myristate, Sorbitol, Xanthan Gum, Sodium PCA, Butylene Glycol, Simethicone, Magnesium Aluminum Silicate, Calcium Pantothenate. Extracts of: Chamomile, Comfrey, Echinacea, Fenugeek, Garlic, Lemon Peel, Propolis, Sage. White Oak Bark, Yarrow, Magnesium Ascorbyl Phosphate, Lactic Acid, Corn (Zea Mays) Oil (and) Retinyl Palmitate (Vitamin A Palmitate) (and) Cholecalciferol (Vitamin D3), Tocopheryl Acetate (Vitamin E Acetate), Sodium Hyaluronate, Phenoxyetanol, Trisodium EDTA, Sodium Benzoate, Methylparaben, Propylparaben, Diazolidinyl Urea.
Step 2: Water, Glyceryl Stearate (and) PEG-100 Stearate, Propylene Glycol, Stearic Acid, Octyl Dimethyl PABA, Sorbitan Sesquioleate, Cetyl Acetate (and) Acetylated Lanolin Alcohol, Cetyl Alcohol, Mineral Oil, Isopropyl Palmitate, Tocopheryl Acetate (Vitamin E Acetate), Dimethicone Xanthan Gum, Sorbic Acid, Sodium Sulfite, Sodium Bisulfite, Sodium Benzoate, Methylparaben, Propylparaben, Diazolidinyl Urea.
Step Three: Aloe Barbadensis Gel (Aloe Vera Gel), Propylene Glycol, Isopropyl Palmitate, Sorbitol, Glyceryl Stearate, Stearic Acid, Cetyl Alcohol, Squalene, Laureth-Four PEG-100 Stearate, Glycolic Acid, Hydrolyzed Elastin, Lactic Acid, Marine Collagen, Hydrolyzed Mucopolysaccharides, Sodium PCA, Sugar Cane Extract, Dimethicone, Polyethylene, Simethicone, Revitalin, Magnesium Aluminum Silicate, Xanthan Gum, Triethanolamine, Trisodium EDTA, Sodium Benzoate, Methylparaben, Propylparaben, Imidazolidinyl Urea, Perfume.

Is Hoof Maker cream for horses really good for your nails?

Kim’s query…Is Hoof maker for horses really good for finger nails? If it’s only a good moisturizer are you able to advocate one other product that may work as nicely?

I checked out the Hoof Maker web site and located that it’s made by the identical firm that makes Mane and Tail. The theme is identical throughout all these merchandise and it goes one thing like this “we originally made these products to take care of horses but amazingly people put them on their hair and skin and found out that they are incredible.”

It’s definitely an fascinating backstory however once you take a look at the precise claims they make for this Hoof Maker product it’s really not that exceptional. Right here’s what they are saying:

“Now you can discover the mystery behind luxuriously soft skin and beautiful nails. The exclusive combination of intensive protein enriched ingredients enables your hands and body to achieve a natural feel while moisturizing dry and cracked skin. Originally developed for horses to moisturize dry, cracked, brittle hooves. Since applied to the hoof by human hands, over time many of those using Hoofmaker on their horses noticed dramatic improvement in the condition of their hands and nails.”

Listed here are a few of their particular claims:

  • Moisturizes dry, cracked pores and skin on arms, ft and different areas of the physique
  • 
Fortifies nails and protects them towards injury, sustaining their power and adaptability
  • Softens and circumstances, deeply penetrating tough, callused areas
  • Restores very important vitamins and important moisture to dry pores and skin and nails in a greaseless components
  • 
A manicure and pedicure in a bottle

I took a take a look at the components and anticipated this to be simply one other typical moisturizing formulation. Nevertheless, I used to be stunned to seek out that it makes use of some pretty unconventional components.

In a regular moisturizer you’d look forward to finding occlusive brokers like petrolatum or mineral oil together with maybe some hydrating brokers like glycerin or hyaluronic acid or another humectant. This product doesn’t use any of these occlusive brokers. As an alternative its primary ingredient is a chloride Quat, particularly distearyldimonium chloride.

This strategy truly is sensible because it’s designed for nails relatively than pores and skin. Pores and skin could be hydrated by locking in moisture however nails are just a little bit totally different. So, fairly than utilizing an occlusive , the primary ingredient is a fatty chloride quat, distearyldimonium chloride. I’ve seen this used earlier than as a result of it has a constructive cost and may persist with pores and skin. The product additionally seems to include a good proportion of glycerin which ought to assist bind moisture to the nail.

Coconut oil can also be excessive on the ingredient listing. We all know how coconut oil is good for hair as a result of it will possibly penetrate into the keratin protein of hair I’ve by no means seen any knowledge that exhibits it could possibly penetrate into nails in an analogous approach however definitely has potential.

And lastly it accommodates a lactate salt which is good for nails in the identical with lactic acid is good.

The one ingredient that appears to be lacking that would make this product even higher is a few type of urea.

So all issues being thought-about that is considerably totally different than a typical pores and skin was to rising lotion. However to Kim’s query then how are you going to discover a comparable product that has a special scent. We did discover a few different merchandise that use an identical matrix of components. Right here they’re.

Curel’s Youth-Protection Moisture Lotion
Water, Glycerin, Distearyldimonium Chloride, Isopropyl Palmitate, Cetearyl Alcohol, Petrolatum, Butyrospermum Parkii (Shea Butter), Salvia Officinalis (Sage) Leaf Extract, Ascorbyl Palmitate (Vitamin C), Tocopheryl Acetate (Vitamin E), Hydrolyzed Collagen, Hydrolyzed Elastin, Corn Starch Modified, Dimethicone, Polypropylene, Beeswax (Apis Mellifera), Capric/Caprylic Stearic Triglyceride, Glyceryl Dilaurate, Alumina, Stearic Acid, Acacia Gum (Acacia Senegal) Extract, Phenoxyethanol, Gelatin, Disodium EDTA, DMDM Hydantoin, Propylparaben, Methylparaben, Titanium Dioxide, Perfume

Gold Bond Final Restoring Pores and skin Remedy Lotion
Water, Hydroxyethyl Urea, Glycerin, Dimethicone, Jojoba Esters, Petrolatum, Glyceryl Stearate, Distearyldimonium Chloride, Aloe Barbadensis Leaf Juice, Cetearyl Alcohol, Methyl Gluceth 20, Behentrimonium Methylsulfate, Cetearyl Alcohol, Butyrospermum (Shea Butter) Extract, Ubiquinone, Ceramide Complicated 2, Palmitoyl Oligopeptide, Cocodimonium Hydroxypropyl Hydrolyzed Rice Protein, Niacinamide, Tocopheryl Acetate, Magnesium Ascorbyl Phosphate, Retinyl Palmitate, PEG 10 Rapeseed Sterol, Hydrolyzed Collagen, Polysorbate 60, Stearamidopropyl PG Dimonium Chloride Phosphate, Propylene Glycol, Steareth 21, Diazolidinyl Urea, Perfume, Methylparaben, Hydrolyzed Jojoba Esters, EDTA (Ethylenediamine-Tetra-Acetic Acid), Propylparaben, Butylene Glycol, C12 15 Alkyl Benzoate, Tribehenin, Potassium Hydroxide

Hoof maker Elements
Water/Aqua/Eau, Distearyldimonium Chloride, Cetyl Alcohol, Stearyl Alcohol, Glycerin, Cocos Nucifera (Coconut) Oil, Stearamidopropyl Dimethylamine Lactate, Cetearyl Alcohol, Polysorbate 60, Steareth-20, Glycine Soja (Soybean) Oil, DMDM Hydantoin, Perfume (Parfum), Methylparaben, Lanolin, PEG-150 Stearate, Propylparaben, Hydrolyzed Collagen Protein, PEG-25 Castor Oil, Sodium Chloride, Allantoin, Olea Europaea (Olive) Fruit Oil, Yellow #5 (CI 19140), Yellow #6 (CI 15985), Benzyl Benzoate, Benzyl Salicylate, Citronellol, Geraniol, Hexyl Cinnamal, Butylphenyl Methylpropional, Limonene, Linalool, Hydroxyisohexyl-Three-Cyxlohexene Carboxaldehyde

Is Hexinol the newest anti-aging miracle?

Priyasha says…I used to be interested in this “Hexinol” know-how vary that the ROC model has been advertising. They are saying it’s a model new anti-aging know-how they found. What precisely this hexinol know-how is, and if in truth its only a foolish anti-aging “ingredient” gimmick or if there’s something substantial right here. 


Right here’s some information from the web site for RoC which, by the best way, is owned by J&J…

“After 7 years of research, RoC® Skincare scientists discovered a molecule that would impact signs of aging skin. This was the birth of HEXINOL® technology…it targets skin concerns associated with aging in a different way than other anti-aging ingredients.”

Listed here are some particular claims they make:

  • Restore elasticity and firmness
  • Enhance radiance
  • Hydrate dry pores and skin
  • Clean the look of effective strains and wrinkles
  • Lighten the look of discoloration

Despite the fact that they are saying that Hexinol works “in a different way than other anti-aging ingredients” these are fairly commonplace claims that sound identical to most different anti-aging components!

We reviewed the ingredient lists for a few the ROC merchandise and located that Hexinol is really simply their trademarked identify for the ingredient Hexylresorcinol.

(BTW, scientists should have HATED this due to the identify. To start with hexinol sounds virtually precisely like “hexanol” which is a special chemical, the alcohol made out of hexane, which has nothing to do with anti-aging. Second, the “hex” identify makes it sound like magic.)

So, what the heck is hexylresorcinol? You could be conversant in it as a result of its been used for a very long time as an antiseptic in merchandise like mouthwashes and throat lozenges. However just lately it’s additionally been proven to have pores and skin lightening properties.

I don’t know if HR was found by J&J as a result of different corporations use these things, most notably Clarins. It’s bought by an organization named Sytheon and I don’t consider there’s something proprietary about it. Their commerce is Synovia HR and their web site does doc three medical exams that point out the molecule has anti-aging properties:

First, in vitro testing exhibits HR inhibits the manufacturing of melanin (36% intercellular and 75% extracellular.) Nevertheless, the check didn’t examine it to something so I don’t know what meaning.

Second, one other in vitro check measured inhibition of the enzymes that convert tyrosine to melanin. This was achieved towards different confirmed pores and skin lightening actives and the outcomes confirmed that HR is best than hydroquinone, licorice and kojic acid.

Third is a human medical research evaluating HR at zero.5% to hydroquinone at 2%. The checks measured two sorts of outcomes.

The primary end result confirmed a better ITA which stands for Particular person Typography Angle. A better ITA signifies higher pores and skin brightening. HR confirmed an enchancment that’s about equal to HQ however because it solely took zero.5% HR to get the identical impact at 2% HQ they get to say that HR is “4x more effective than HR.” That appears a bit deceptive to me as a result of it implies that it makes pores and skin Four occasions lighter than HQ and that’s not the case in any respect.

The second outcome was labeled merely as “% improvement in skin brightening” which doesn’t inform us something about how the check was achieved. In any occasion, HR did about in addition to HQ.

When wanting for proof of how an ingredient works you by no means need to solely depend on info from the provider so we discovered that HR has been reviewed by different evidence-based magnificence blogs just like the Beauty Cop and Fact in Getting old. Right here’s what Paula Begon says…

“Hexylresorcinol is a synthetic ingredient that has been shown to have skin lightening ability in cell cultures but there is very limited research about it on skin. It is mostly an antioxidant, antiseptic and anesthetic.”

She additionally cited a research revealed in a 2013 version of Journal of Medicine in Dermatology and stated that…

“This study is often quoted as saying it worked better than or as well as 4% hydroquinone but 4 weeks is not long enough to judge that and again, and this was not about hexylresorcinol itself .”

Lastly, the web site Fact in Getting old says…

”HR’s capacity to focus on pathways within the pores and skin that result in hyperpigmentation has propelled it into the pores and skin lightening ingredient class. There’s additionally thought that Hexylresorcinol has extra advantages as nicely, together with a capability to scale back the looks of high quality strains and wrinkles, improve safety towards UVB and UVA rays, and enhance the pores and skin’s barrier towards air pollution and solar publicity.”

Sadly, the hyperlink to a supply of their info didn’t work so I’m unsure the place that information got here from. (However I see that the provider’s web site makes a few of these similar claims.)

What’s the underside line about HR? It seems to be a promising ingredient however we haven’t seen sufficient proof to recommend that it’s higher than different confirmed options. In the event you’re wanting for one thing new to attempt to you don’t thoughts the worth, then I don’t see any purpose to not give Hexinol an opportunity.

Ingredient lists for ROC merchandise
Water, Glycerin, Cetyl Alcohol, Nylon 12, Dimethicone, Ethylhexyl Hydroxystearate, Ethylhexyl Palmitate, Glyceryl Stearate, Hexyldecyl Stearate, PEG 100 Stearate, Sorbitan Stearate, Phenoxyethanol, Mica, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Butyrospermum Parkii (Shea) Butter, Hexylresorcinol, Titanium Dioxide, Isohexadecane, Perfume, Methylparaben, Polysorbate 80, Acrylates/C10 30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Tocopheryl, Sucrose Cocoate, Ascorbic Acid, Panthenol, Sodium Hydroxide, Saccharomyces Cerevisiae Extract

Water, Glycerin, Cetyl Alcohol, Nylon 12, Dimethicone, Ethylhexyl Hydroxystearate, Ethylhexyl Palmitate, Glyceryl Stearate, Hexyldecyl Stearate, PEG 100 Stearate, Sorbitan Stearate, Phenoxyethanol, Mica, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Butyrospermum Parkii (Shea) Butter, Hexylresorcinol, Titanium Dioxide, Isohexadecane, Perfume, Methylparaben, Polysorbate 80, Acrylates/C10 30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Tocopheryl, Sucrose Cocoate, Ascorbic Acid, Panthenol, Sodium Hydroxide, Saccharomyces Cerevisiae Extract

iTunes Evaluations

Abcfg says… Informative, humorous, and related!

Kublakaan says….I love their nerdy, scientific, non-biased means of explaining the good and dangerous of magnificence merchandise. They clearly have a agency grasp on statistical evaluation, knowledge evaluation, and clearly chemistry.  Regardless of all the exhausting science, they’re is straightforward to perceive, and even humorous. I’m a a lot wiser and selective shopper now that I can higher spot the advertising traps that magnificence corporations use to milk us of our cash!

Unbelievable Merchandise

I learn an article on 6 loopy spa remedies however they only weren’t loopy sufficient. So I made up one in every of my very own. You guys need to guess which is the pretend.

Hen soup sauna
One Spa chain within the southern US will soak you in heat hen soup which is wealthy in fat and proteins that nourish the pores and skin.

Hearth facial
This Chinese language remedy makes use of a cool burning alcohol flame to stimulate pores and skin and battle indicators of growing older.

Butter tub
In Ethiopian spas, ladies moisturize pores and skin by rubbing butter throughout your physique after which melting it away with smoke.

Take heed to the present for the reply!

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